Arabidopsis 2010: Towards a comprehensive Arabidopsis protein interactome map: Systems biology of the membrane proteins and signalosomes

Biological systems function through interactions of proteins with other macromolecules (proteins, DNA, RNA, complex carbohydrates and lipids), and with small molecules, including metabolites and secondary compounds. Membranes provide a surface for perceiving and transducing signals from adjacent cells and external conditions such as availability of nutrients, or toxins and adverse conditions for growth and development. In addition, membranes control cellular and subcellular entry and exit of molecules. To understand the regulation of cell-environment, cell-cell, and intracellular compartment to cytosol interactions better, we plan to determine the interactions of 6,400 proteins(excel format) from the reference plant Arabidopsis. This set comprises essentially all integral membrane proteins (>5,000) and a large number (>1,000) of proteins predicted to be involved in signaling or protein modification. Read more.

Notices:

[9/14/07] New look and feel of our website: We changed the home page and navigation structure to facilitate data access.

[9/14/07] Full-length ORF clones for membrane or signaling proteins wanted: If you have any Arabidopsis membrane or signaling proteins in Gateway Entry Vectors and want them to be included in our interaction assays, read more. Contact: Sylvie Lalonde (slalondestanford.edu)